Promethazine codeine syrup - An Overview
Promethazine codeine syrup - An Overview
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The codeine and promethazine in Promethazine with Codeine Oral Solution may perhaps enhance the frequency of seizures in patients with seizure disorders, and could raise the hazard of seizures transpiring in other medical options related to seizures.
Constipation is a typical side impact of the two codeine and hydrocodone use and sometimes continues through treatment method. Folks may possibly get stool softeners and raise their fluid ingestion to help you lower this aspect outcome.
Ideal scientific studies have not been performed on the connection of age to the effects of codeine inside the pediatric population. It shouldn't be Employed in small children youthful than twelve many years of age. Safety and efficacy haven't been founded.
The concomitant use of Promethazine with Codeine Oral Alternative with all cytochrome P450 3A4 inducers or discontinuation of a cytochrome P450 3A4 inhibitor may possibly cause reduce codeine ranges, increased norcodeine ranges, and fewer metabolism by using 2D6 with resultant reduced morphine levels. This can be connected with a lessen in efficacy, and in some clients, may possibly end in signals and signs and symptoms of opioid withdrawal.
This product might have inactive elements, which often can lead to allergic reactions or other problems. Speak to your pharmacist for more facts.
Promethazine with Codeine Oral Answer consists of promethazine, a phenothiazine. Phenothiazines are associated with dystonic reactions, particularly in pediatric people who may have an acute health issues linked to dehydration.
Thoroughly measure the dose utilizing a Unique measuring system/spoon. Do not utilize a residence spoon as you may not get the right dose.
The existence of Promethazine codeine syrup other clinical troubles may possibly have an impact on using this drugs. Be sure you inform your doctor When you have some other medical difficulties, Particularly:
The next serious adverse reactions are described, or described in larger element, in other sections:
If this SPL incorporates inactivated NDCs stated by the FDA initiated compliance motion, they will be specified as such.
Codeine causes a discount in motility connected to a rise in easy muscle mass tone during the antrum in the belly and duodenum. Digestion of food stuff from the compact intestine is delayed and propulsive contractions are lowered.
For the reason that opioid agonists might raise biliary tract tension, with resultant rise in plasma amylase or lipase amounts, dedication of those enzyme stages may very well be unreliable for twenty-four hrs after administration of the dose of Promethazine with Codeine Oral Answer.
Applying alcohol or tobacco with certain medicines might also bring about interactions to happen. The next interactions are already picked on The idea in their probable significance and so are not necessarily all-inclusive.
Most MAO inhibitors also needs to not be taken for 2 weeks just before treatment with this particular medication. Question your health care provider when to begin or prevent using this medication.